If hectic holiday preparations are giving you a headache, perhaps it’s time for Cascarets. 5 million boxes of headache remedy sold must mean something, right? From the Skidmore Standard (Skidmore, Missouri), December 15, 1899, page 7:

“Headache. Sick headaches! Always trace them to a lazy liver or a sick stomach. Poisonous matter, instead of being thrown out, is reabsorbed into the blood. When this poison reaches the delicate brain tissue it causes congestion and that dull, awful, throbbing, sickening pain. Cascarets remove the cause by stimulating the liver, making the poison move on and out, and purifying the blood. The effect is almost instantaneous. Ladies, whose sensitive organisms are especially prone to sick headaches, do not suffer, but find relief in Cascarets Candy Cathartic.”